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Job satisfaction has been a recurring problem amongst nurses in Nigeria. As such, unfavourable working conditions are compounding problems of shortage and anticipated turnover among the Nigerian nursing workforce. This study assessed the factors influencing job satisfaction among nurses in Ahmadu Bello University Teaching Hospital (ABUTH), Zaria, Kaduna State, Nigeria. A quantitative descriptive cross-sectional design was adopted for the study, and stratified random sampling technique was used to select a sample of 360 participants from a population of 695 nurses. Revised Nursing Work Index (NWI- R) questionnaire was adopted as the data collection tool, and data was analysed using Statistical Package for Social Science (SPSS) Version 21.0. The major causes of job dissatisfaction among the participants were poor salary, working conditions and staffing. The study recommends that ABUTH management should improve upon nurses' remuneration, create a healthy practising environment and improve their staffing of nurses to retain the practising nurses and attract the younger generation into the profession.